Regulatory Compliance
Animal Care & Use


Why Animal Research Matters

Scientists use a variety of ways to expand our fundamental knowledge of biology, human nature, society, and the natural world. These methods include computer simulations, cell cultures (in vitro work), human volunteers in clinical trials, and animal models.

There is still a lot about the human body and about the world around us that we do not yet fully understand – Animal research is one such indispensable approach for increasing our understanding about complex living organisms. These highly regulated studies with animals are often the last step before research can involve human subjects, and are used to help validate results of decade-long research projects. 

See UCI Statement on the Use of Animals in Research and Teaching

See UCOP's Position Statement on Animal Research

About our IACUC

UC Irvine’s IACUC (Institutional Animal Care and Use Committee) is composed of scientists, non-scientists, veterinarians and community members – all appointed by the Vice Chancellor for Research. This committee oversees all aspects of the Animal Care and Use program at UCI. Community members are individuals who are not affiliated with the university and help to provide an outsider perspective, representing the views of the general public.

The university is charged by federal animal welfare regulations, U.S. Public Health Service (PHS) Policy, and accreditation standards with the responsibility to assure that:

  • The use of live, vertebrate animals in research, testing, teaching or related activities is scientifically justified;
  • All animals intended for use in those activities are provided humane care and treatment, including appropriate veterinary medical care
  • Procedures are designed to minimize or avoid pain, distress and discomfort
  • All personnel involved in the use of animals have received appropriate training to conduct the procedures and care for the animals.

The IACUC works closely with University Laboratory Animal Resources (ULAR) and Environmental Health & Safety (EH&S) to ensure the well-being of animals and safety of researchers.

Do you need IACUC review?

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Report Animal Welfare Concern


Questions about working with animals? Email us at


IACUC Meetings & Deadlines

Full Committee Calendar

Related Information:

IACUC News & Announcements

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Fast Facts

USDA Registration #93-R-0434

PHS Assurance D16-00259 (A3416-01)
2/3/20 – 2/28/24

AAALAC #000238
Current Accreditation 2018-2021
Full Accreditation since 1971